Synthase

TVB-3664 View larger

TVB-3664

AT17181

CAS 2097262-58-1

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$120.00

$120.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $54.00 Total: $5,400.00
150 $62.40 Total: $3,120.00
125 $73.20 Total: $1,830.00
110 $86.40 Total: $864.00
15 $102.00 Total: $510.00

Data sheet

Molecular FormulaC25H23F3N4O2
Molecular Weight468.47
CAS Numbers2097262-58-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOCc1nc([nH]c1-c1cc(C(=O)N2CC(C2)c2ccc(cc2)C#N)c(C)cc1C)C(F)(F)F
ReferencesZaytseva YY, et al. Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer. Oncotarget. 2018 May 15;9[37] 24787-24800.

More info

TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively).