TNF Receptors

AX-024 hydrochloride View larger

AX-024 hydrochloride

AT4403

CAS 1704801-24-0

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$44.00

$44.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.80 Total: $1,980.00
150 $22.88 Total: $1,144.00
125 $26.84 Total: $671.00
110 $31.68 Total: $316.80
15 $37.40 Total: $187.00

Data sheet

Molecular FormulaC21H23ClFNO2
Molecular Weight375.87
CAS Numbers1704801-24-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.COc1ccc2OCC(CN3CCCC3)=C(c3ccc(F)cc3)c2c1
ReferencesBorroto A, etal. First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases. Sci Transl Med. 2016 Dec 21;8[370] 370ra184.

More info

AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-? (TNF?), interferon-? (IFN-?), IL-10 and IL-17A.