TNF Receptors

Resatorvid View larger

Resatorvid

ATQ0181

CAS 243984-11-4

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$38.00

$38.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.10 Total: $1,710.00
150 $19.76 Total: $988.00
125 $23.18 Total: $579.50
110 $27.36 Total: $273.60
15 $32.30 Total: $161.50

Data sheet

Molecular FormulaC15H17ClFNO4S
Molecular Weight361.82
CAS Numbers243984-11-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCOC(=O)C1=CCCC[C@H]1S(=O)(=O)Nc1ccc(F)cc1Cl
ReferencesZandi Z, et al. The anticancer effect of the TLR4 inhibition using TAK-242 [resatorvid] either as a single agent or in combination with chemotherapy A novel therapeutic potential for breast cancer. J Cell Biochem. 2020 Feb;121[2] 1623-1634.

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Resatorvid (TAK-242), a selective Toll-like receptor 4 (TLR4) inhibitor, binds directly to Cys747 to prevent TLR4-TIRAP interaction, thereby blocking downstream signaling. Resatorvid exhibits antitumor, anti-inflammatory, and neuroprotective activities.