TNF Receptors

GIBH-130 View larger

GIBH-130

AT4450

CAS 1252608-59-5

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$32.00

$32.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.40 Total: $1,440.00
150 $16.64 Total: $832.00
125 $19.52 Total: $488.00
110 $23.04 Total: $230.40
15 $27.20 Total: $136.00

Data sheet

Molecular FormulaC20H20N6O
Molecular Weight360.41
CAS Numbers1252608-59-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1cc(nnc1C(=O)N1CCN(CC1)c1ncccn1)-c1ccccc1
ReferencesZhou W, Zhong G, Fu S, et al. Microglia-Based Phenotypic Screening Identifies a Novel Inhibitor of Neuroinflammation Effective in Alzheimer's Disease Models[J]. Acs Chemical Neuroscience, 2016, 7[11] 1499-1507.

More info

GIBH-130 markedly inhibits the IL-1? secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.