TNF Receptors

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea View larger

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea

AT60124

CAS 2379727-88-3

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$99.00

$99.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $44.55 Total: $4,455.00
150 $51.48 Total: $2,574.00
125 $60.39 Total: $1,509.75
110 $71.28 Total: $712.80
15 $84.15 Total: $420.75

Data sheet

Molecular FormulaC24H21ClF3N5O
Molecular Weight487.9
CAS Numbers2379727-88-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C(NC1=CC(C(F)(F)F)=C(Cl)C=C1)=O)C2CC=3C=4C(NC3CC2)=CC(=CC4)C5=CN(C)N=C5
ReferencesPei H, et al. Discovery of potent ureido tetrahydrocarbazole derivatives for cancer treatments through targeting tumor-associated macrophages. Eur J Med Chem. 2019 Dec 1;183 111741.

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1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-? agonistic compound, could induce cells to secrete TNF- ?.