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Topoisomerase
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View larger Pyrazoloacridine
AT28475
CAS 99009-20-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Data sheet
| Molecular Formula | C19H21N5O3 |
| Molecular Weight | 367.4 |
| CAS Numbers | 99009-20-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc2[nH]c3c(ccc4n(CCCN(C)C)nc(c34)c2c1)[N+]([O-])=O |
| References | Chen DS, et al. Combinatorial synthesis of pyrazoloquinoline and pyrazoloacridine derivatives with high regioselectivity. Comb Chem High Throughput Screen. 2013 Jun 28;16[7] 550-61. |
More info
Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 ?M in K562 cells. Pyrazoloacridine shows anti-cancer activity.