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Topoisomerase
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View larger Levofloxacin hydrochloride
AT8747
CAS 177325-13-2
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Data sheet
| Molecular Formula | C18H21ClFN3O4 |
| Molecular Weight | 397.8 |
| CAS Numbers | 177325-13-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O |
| References | Schmitz FJ, et al. J Antimicrob ChemOthers. 1998 Apr;41[4] 481-4. |
More info
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.