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ML334 View larger

ML334

AT12078

CAS 1432500-66-7

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$42.00

$42.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.90 Total: $1,890.00
150 $21.84 Total: $1,092.00
125 $25.62 Total: $640.50
110 $30.24 Total: $302.40
15 $35.70 Total: $178.50

Data sheet

Molecular FormulaC26H26N2O5
Molecular Weight446.49
CAS Numbers1432500-66-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)[C@H]1CCCC[C@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)c2ccccc2C1=O
ReferencesHu L, et al. Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction. Bioorg Med Chem Lett. 2013 May 15;23[10] 3039-43.

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ML334 (LH601A) is a transmembrane and potent NRF2 activator that inhibits Keap1-NRF2 protein interactions to ameliorate myocardial infarction-induced cardiac fibrosis by inhibiting cardiac fibroblast activation and proliferation.