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Icenticaftor View larger

Icenticaftor

AT9499

CAS 1334546-77-8

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$231.00

$231.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $103.95 Total: $10,395.00
150 $120.12 Total: $6,006.00
125 $140.91 Total: $3,522.75
110 $166.32 Total: $1,663.20
15 $196.35 Total: $981.75

Data sheet

Molecular FormulaC12H13F6N3O3
Molecular Weight361.24
CAS Numbers1334546-77-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1nc(C(=O)NC[C@](C)(O)C(F)(F)F)c(N)cc1C(F)(F)F
ReferencesDarren Le Grand, et al. Discovery of Icenticaftor [QBW251], a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. J Med Chem. 2021 Jun 10;64[11] 7241-7260.

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Icenticaftor (QBW251) is an orally active potentiator of the CFTR channel.