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View larger Bamocaftor
AT30293
CAS 2204245-48-5
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $268.60 | Total: $1,343.00 |
| 1 | 10 | $227.52 | Total: $2,275.20 |
| 1 | 25 | $192.76 | Total: $4,819.00 |
| 1 | 50 | $164.32 | Total: $8,216.00 |
| 1 | 100 | $142.20 | Total: $14,220.00 |
Data sheet
| Molecular Formula | C28H32F3N5O4S |
| Molecular Weight | 591.65 |
| CAS Numbers | 2204245-48-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2ccccc2)-n2ccc(OCCC3(CC3)C(F)(F)F)n2)C(C)(C)C1 |
| References | Ghelani DP, et al. Emerging Cystic Fibrosis Transmembrane Conductance Regulator Modulators as New Drugs for Cystic Fibrosis A Portrait of in Vitro Pharmacology and Clinical Translation. ACS Pharmacol Transl Sci. 2019;3[1] 4-10. |
More info
Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function. Combined use of tezacaftor and VX-561 for the treatment of cystic fibrosis patients with F508delMF.