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View larger CDDO-dhTFEA
AT13604
CAS 1191265-33-4
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C33H45F3N2O3 |
| Molecular Weight | 574.72 |
| CAS Numbers | 1191265-33-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)NCC(F)(F)F |
| References | Aminzadeh MA, et al. The synthetic triterpenoid RTA dh404 [CDDO-dhTFEA] restores endothelial function impaired by reduced Nrf2 activity in chronic kidney disease. Redox Biol. 2013 Oct 31;1 527-31. |
More info
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-?B pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-?B and transforming growth factor-? pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).