Transcription Factors

SRI-37240 View larger

SRI-37240

AT61702

CAS 883956-47-6

More details

Molarity Calculation Cart®

HOW TO ORDER

$30.00

$30.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.50 Total: $1,350.00
150 $15.60 Total: $780.00
125 $18.30 Total: $457.50
110 $21.60 Total: $216.00
15 $25.50 Total: $127.50

Data sheet

Molecular FormulaC24H23N3O2
Molecular Weight385.46
CAS Numbers883956-47-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C=2C=CC=CC2N(C=3N=C(C=4C=CC=CC4)N(C(=O)C13)C5CCCCC5)C
ReferencesSharma J, et al. A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion. Nat Commun. 2021 Jul 16;12[1] 4358.

More info

SRI-37240 is a potent inhibitor of premature termination codons (PTCs) with read-across activity that induces a prolonged pause at the termination codon and inhibits PTCs associated with cystic fibrosis.SRI-37240 can be used to study PTC-related diseases.