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2-tert-Butyl-1,4-benzoquinone View larger

2-tert-Butyl-1,4-benzoquinone

ATN6750

CAS 3602-55-9

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Data sheet

Molecular FormulaC10H12O2
Molecular Weight164.2
CAS Numbers3602-55-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)(C)C1=CC(=O)C=CC1=O
ReferencesAbiko Y, Kumagai Y. Interaction of Keap1 modified by 2-tert-butyl-1,4-benzoquinone with GSH evidence for S-transarylation. Chem Res Toxicol. 2013 Jul 15;26[7] 1080-7.

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2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), activates Nrf2 and S-arylates its negative regulator Keap1 in RAW264.7 cells.