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Transporter Inhibitors

S0859 Sodium View larger

S0859 Sodium

AOB1489

CAS No: 1019331-10-2 (Free Na Form)

Chemical Name: Sodium 2-chloro-N-[[2'-[(cyanoamino)sulfonyl][1,1'-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $8.50 Total: $42.50
110 $7.20 Total: $72.00
125 $6.10 Total: $152.50
150 $5.20 Total: $260.00
1100 $4.50 Total: $450.00

Data sheet

Molecular FormulaC29H23ClN3NaO3S
Molecular Weight552.02
CAS Numbers1019331-10-2 (Sodium free)
Storage Condition+4C
IUPAC/Chemical NameSodium 2-chloro-N-[[2'-[(cyanoamino)sulfonyl][1,1'-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide
InChl KeyITDBPOSLOROLMT-UHFFFAOYSA-N
InChl CodeInChI=1S/C29H24ClN3O3S/c1-21-10-12-22(13-11-21)18-33(29(34)26-7-2-4-8-27(26)30)19-23-14-16-24(17-15-23)25-6-3-5-9-28(25)37(35,36)32-20-31/h2-17,32H,18-19H2,1H3
SMILES CodeCC(C=C1)=CC=C1CN(C(C2=CC=CC=C2Cl)=O)CC(C=C3)=CC=C3C(C=CC=C4)=C4S(NC#N)(=O)=O
References1) Ch'en, F.F.T., Villafuerte, F.C., Swietach, P., et al. S0859, an N-cyanosulphonamide inhibitor of sodium-bicarbonate cotransport in the heart. British Journal of Pharmacology 153, 972-982 (2008).

2) Yamamoto, T., Swietach, P., Rossini, A., et al. Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig. Journal of Physiology 562.2, 455-475 (2005).

More info

Selective, high-affinity generic NBC inhibitor; Selective sodium bicarbonate co-transport inhibit