Ubiquitin-Activating Enzyme

GSK2643943A View larger

GSK2643943A

AT11485

CAS 2449301-27-1

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$32.00

$32.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.40 Total: $1,440.00
150 $16.64 Total: $832.00
125 $19.52 Total: $488.00
110 $23.04 Total: $230.40
15 $27.20 Total: $136.00

Data sheet

Molecular FormulaC17H12FN3
Molecular Weight277.3
CAS Numbers2449301-27-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNc1[nH]c2cc(C=Cc3cccc(F)c3)ccc2c1C#N
ReferencesHarrigan JA, et al.Deubiquitylating enzymes and drug discovery emerging opportunities.Nat Rev Drug Discov. 2018 Jan;17[1] 57-78.

More info

GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20Ub-Rho. GSK2643943A has anti-tumor efficacy.