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Ubiquitin-Activating Enzyme
- Protein Control Ligand
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View larger GSK2643943A
AT11485
CAS 2449301-27-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Data sheet
| Molecular Formula | C17H12FN3 |
| Molecular Weight | 277.3 |
| CAS Numbers | 2449301-27-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Nc1[nH]c2cc(C=Cc3cccc(F)c3)ccc2c1C#N |
| References | Harrigan JA, et al.Deubiquitylating enzymes and drug discovery emerging opportunities.Nat Rev Drug Discov. 2018 Jan;17[1] 57-78. |
More info
GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20Ub-Rho. GSK2643943A has anti-tumor efficacy.