Votage-Gated Ion Channel Blockers

AqB011 View larger

AqB011 Hydrochloride

AOB10770

CAS No: 1021869-49-7 (Free Base)

 

Chemical Name: 3-Butylamino-4-phenoxy-N-pyridin-3-ylmethyl-5-sulfamoyl-benzamide Hydrochloride

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$39.50

$39.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.78 Total: $1,777.50
150 $20.54 Total: $1,027.00
125 $24.10 Total: $602.38
110 $28.44 Total: $284.40
15 $33.58 Total: $167.88

Data sheet

Molecular FormulaC23H26N4O4S HCl
Molecular Weight491.00
CAS Numbers1021869-49-7 (Free Base)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymAqB011; AqB-011; AqB 011
IUPAC/Chemical Name3-Butylamino-4-phenoxy-N-pyridin-3-ylmethyl-5-sulfamoyl-benzamide Hydrochloride
References1) Kourghi M, De Ieso ML, Nourmohammadi S, Pei JV, Yool AJ. Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the Ionic Conductance and Inhibition by AqB011. Front Chem. 2018 Apr 27;6:142.

2) Kourghi M, Pei JV, De Ieso ML, Nourmohammadi S, Chow PH, Yool AJ. Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life. Clin Exp Pharmacol Physiol. 2018 Apr;45(4):401-409.

More info

Selective blocker of the Aquaporin-1 ion channel conductance, slowing cancer cell migration