Votage-Gated Ion Channel Blockers

Zoniporide hydrochloride View larger

Zoniporide hydrochloride

AT21996

CAS 241800-97-5

More details

Molarity Calculation Cart®

HOW TO ORDER

$48.00

$48.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.60 Total: $2,160.00
150 $24.96 Total: $1,248.00
125 $29.28 Total: $732.00
110 $34.56 Total: $345.60
15 $40.80 Total: $204.00

Data sheet

Molecular FormulaC17H17ClN6O
Molecular Weight356.81
CAS Numbers241800-97-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.O=C(NC(=N)N)C=1C=NN(C2=CC=CC3=NC=CC=C32)C1C4CC4
ReferencesGuzman-Perez A, et al. Discovery of zoniporide a potent and selective sodium-hydrogen exchanger type 1 [NHE-1] inhibitor with high aqueous solubility. Bioorg Med Chem Lett. 2001 Mar 26;11[6] 803-7.

More info

Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.