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Votage-Gated Ion Channel Blockers
- Protein Control Ligand
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Data sheet
| Molecular Formula | C17H18ClN3O |
| Molecular Weight | 315.8 |
| CAS Numbers | 1395946-75-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1 |
| References | Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8[43] 74217-74232. |
More info
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 ?M, 0.57 ?M, and 0.63 ?M for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.