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Votage-Gated Ion Channel Blockers
- Protein Control Ligand
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- Protease
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- p18
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- p53
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- Ubiquitin-Activating Enzyme
- Adenosine Deaminase
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $53.55 | Total: $5,355.00 |
| 1 | 50 | $61.88 | Total: $3,094.00 |
| 1 | 25 | $72.59 | Total: $1,814.75 |
| 1 | 10 | $85.68 | Total: $856.80 |
| 1 | 5 | $101.15 | Total: $505.75 |
Data sheet
| Molecular Formula | C14H12N2O2 |
| Molecular Weight | 240.26 |
| CAS Numbers | 1800405-30-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1nc-2c([nH]1)C(=O)C(=O)c1ccccc-21 |
| References | Seo KS, et al. KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. Front Neurol. 2018 Jul 5;9 552. |
More info
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1?. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.