Votage-Gated Ion Channel Blockers

RN9893 View larger

RN9893

AT28548

CAS 1803003-68-0

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$33.00

$33.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.85 Total: $1,485.00
150 $17.16 Total: $858.00
125 $20.13 Total: $503.25
110 $23.76 Total: $237.60
15 $28.05 Total: $140.25

Data sheet

Molecular FormulaC21H23F3N4O5S
Molecular Weight500.49
CAS Numbers1803003-68-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(NC1=CC=C(S(=O)(=O)N2CCN(C(C)C)CC2)C=C1)(=O)C3=C(N(=O)=O)C=C(C(F)(F)F)C=C3
ReferencesWei ZL, et al. Identification of orally-bioavailable antagonists of the TRPV4 ion-channel. Bioorg Med Chem Lett. 2015 Sep 15;25[18] 4011-5.

More info

RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.