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Votage-Gated Ion Channel Blockers
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C13H12FN3O2 |
| Molecular Weight | 261.25 |
| CAS Numbers | 852146-73-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1=C(C=2OC(C(NC(=N)N)=O)=CC2)C=C(F)C=C1 |
| References | Roh HY, et al. Cardioprotective effects of [5-[2-methyl-5-fluorophenyl]furan-2-ylcarbonyl]guanidine [KR-32568] in an anesthetized rat model of ischemia and reperfusion heart injury. Pharmacology. 2005;75[1] 37-44. |
More info
KR-32568 is a sodiumhydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 ?M, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mgkg) reduced myocardial infarction size in a rat model of ischemia and reperfusion injury.