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View larger PF-4840154
AT4385
CAS 1332708-14-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $79.90 | Total: $399.50 |
| 1 | 10 | $67.68 | Total: $676.80 |
| 1 | 25 | $57.34 | Total: $1,433.50 |
| 1 | 50 | $48.88 | Total: $2,444.00 |
| 1 | 100 | $42.30 | Total: $4,230.00 |
Data sheet
| Molecular Formula | C26H38N6O2 |
| Molecular Weight | 466.62 |
| CAS Numbers | 1332708-14-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)CNc1nc(ncc1C(=O)NCc1ccccc1)N1CCN(CC2CCCOC2)CC1 |
| References | Ryckmans T,etal.Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.Bioorg Med Chem Lett. 2011 Aug 15;21[16] 4857-9. |
More info
PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel, eliciting TrpA1-mediated nocifensive behavior in mouse, with EC50 values of 97 nM and 23 nM for [rTrpA1] and [hTrpA1], respectively.