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View larger HC067047 Hydrochloride(883031-03-6 free base)
AT4680L
CAS 1481646-76-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $50.85 | Total: $5,085.00 |
| 1 | 50 | $58.76 | Total: $2,938.00 |
| 1 | 25 | $68.93 | Total: $1,723.25 |
| 1 | 10 | $81.36 | Total: $813.60 |
| 1 | 5 | $96.05 | Total: $480.25 |
Data sheet
| Molecular Formula | C26H29ClF3N3O2 |
| Molecular Weight | 507.98 |
| CAS Numbers | 1481646-76-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C1=C(C)N(CCCN2CCOCC2)C(C3=CC=CC=C3)=C1)NC4=CC=CC(C(F)(F)F)=C4.[H]Cl |
| References | Xing Y , Ming J , Liu T , et al. Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment[J]. Yonsei medical journal, 2018, 59[9]. |
More info
HC-067047 hydrochloride is a potent and selective TRPV4 antagonist, effectively and reversibly inhibiting currents through human, rat, and mouse TRPV4 orthologs with IC50 values of 486 nM, 133 nM, and 17 nM, respectively.