Votage-Gated Ion Channel Blockers

TRPM8 antagonist WS-3 View larger

TRPM8 antagonist WS-3

AT5962

CAS 39711-79-0

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Data sheet

Molecular FormulaC13H25NO
Molecular Weight211.34
CAS Numbers39711-79-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(NCC)(=O)C1C(C(C)C)CCC(C)C1
ReferencesH?J Behrendt, Germann T , Gillen C , et al. Characterization of the mouse cold?menthol receptor TRPM8 and vanilloid receptor type?1 VR1 using a fluorometric imaging plate reader [FLIPR] assay[J]. British Journal of Pharmacology, 2004, 141[4].

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TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 ?M).