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AOB14298
CAS No: 592474-91-4
Chemical Name: 1-
Warning: Last items in stock!
Availability date: 12/15/2017
Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $16.65 | Total: $1,665.00 |
1 | 50 | $19.24 | Total: $962.00 |
1 | 25 | $22.57 | Total: $564.25 |
1 | 10 | $26.64 | Total: $266.40 |
1 | 5 | $31.45 | Total: $157.25 |
Molecular Formula | C16H9BrF6N6O |
Molecular Weight | 495.18 |
CAS Numbers | 265646-85-3 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSA: 10 mg/mL |
Purity | 98% by HPLC |
A di-aryl-urea-based reversible anion channel blocker that is shown to inhibit Ca(2+)-independent Cl- conductance by volume-regulated anion channel (VRAC or VSOAC; IC50 = 400 nM) as well as Ca2+-activated Cl- ccurrent (CaCC) by anoctamin (ANO) in an apparently voltage-dependent manner (IC50 against ANO1 = 2.1 and 0.7 μM at -95 and +50 mV, respectively). NS3728 is reported to be 5.5-times more potent than Tamoxifen against VRAC (IC50 = 0.4 vs. 2.2 μM).