AChE

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SAK3

AT26174

CAS 1256269-87-0

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$110.00

$110.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $49.50 Total: $4,950.00
150 $57.20 Total: $2,860.00
125 $67.10 Total: $1,677.50
110 $79.20 Total: $792.00
15 $93.50 Total: $467.50

Data sheet

Molecular FormulaC20H23N3O4
Molecular Weight369.41
CAS Numbers1256269-87-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(OCC)C=1C(=O)CC2(C(=O)N=C3C(=CC=CN32)C)C1N4CCCCC4
ReferencesYasushi Yabuki, et al. Pharmacological properties of SAK3, a novel T-type voltage-gated Ca2+ channel enhancer. Neuropharmacology. 2017 May 1;117 1-13.

More info

SAK3 is a novel modulator of nAChR activity that enhances T-type voltage-gated Ca2+ channel (T-VGCC) activity, and has potentiating effects on both Cav3.1 and Cav3.3 T-type Ca2+ channel currents.SAK3 is neuroprotective against scopolamine-induced cholinergic dysfunction in human neuroblastoma SH-SY5Y cells.SAK3 is used for the study of memory deficits and Alzheimer's disease. SAK3 can be used to study memory deficits and Alzheimer's disease.