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FKGK18

Cat No: AOB4846

Condition

CAS No: 1071001-09-6

Chemical Name: 1,1,1-Trifluoro-6-(2-naphthalenyl)-2-hexanone

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$18.70	Total: $93.50
1	10	$15.84	Total: $158.40
1	25	$13.42	Total: $335.50
1	50	$11.44	Total: $572.00
1	100	$9.90	Total: $990.00

Data sheet

Molecular Formula	C16H15F3O
Molecular Weight	280.28
CAS Numbers	1071001-09-6
Synonym	FKGK18; FKGK-18; FKGK 18
IUPAC/Chemical Name	1,1,1-trifluoro-6-(2-naphthalenyl)-2-hexanone
InChl Key	VCWWTQMRNJSJGC-UHFFFAOYSA-N
InChl Code	InChI=1S/C16H15F3O/c17-16(18,19)15(20)8-4-1-5-12-9-10-13-6-2-3-7-14(13)11-12/h2-3,6-7,9-11H,1,4-5,8H2
SMILES Code	O=C(C(F)(F)F)CCCCC1=CC2=CC=CC=C2C=C1
References	1) Kokotos, G., et al. Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2. J. Med. Chem. 53(9), 3602-3610 (2010). 2) Ali, T., et al. Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): Candidate drug for preventing β-cell apoptosis and diabetes. PLoS One 8(8):e71748, (2013). 3) Bone, R.N., et al. Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice. Diabetes 64(2), 541-554 (2015).