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Calcium Channel
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Fluspirilene
AOB33780
CAS: 1841-19-6
Chemical Name: 8-[4,4-Bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; R 6218; Redeptin; Imap; Spirodiflamine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $8.55 | Total: $855.00 |
| 1 | 50 | $9.88 | Total: $494.00 |
| 1 | 25 | $11.59 | Total: $289.75 |
| 1 | 10 | $13.68 | Total: $136.80 |
| 1 | 5 | $16.15 | Total: $80.75 |
Data sheet
| Molecular Formula | C29H31F2N3O |
| Molecular Weight | 475.57 |
| CAS Numbers | 1841-19-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO and Water |
| Stock Solution Guide | 5 mMol/2.4 mg/1 mL; 10 mMol/4.76 mg/1 mL of Solvent |
| Purity | 98% by HPLC |
| Synonym | McN-JR 6218; R 6218; Redeptin |
| IUPAC/Chemical Name | 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| InChl Key | QOYHHIBFXOOADH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) |
| SMILES Code | FC1=CC=C(C(C2=CC=C(F)C=C2)CCCN3CCC4(C(NCN4C5=CC=CC=C5)=O)CC3)C=C1 |
| References | 1) Kenny, B.A., Fraser, S., Kilpatrick, A.T., et al. Selective antagonism of calcium channel activators by fluspirilene. Br. J. Pharmacol. 100(2), 211-216 (1990). 2) Enyeart, J.J., and Enyeart, J.A. Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion. Am. J. Physiol. Cell Physiol. 308(11), C899-C918 (2015). |
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A calcium channel blocker
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