Chromatin Modifying Enzymes

UNC0379 View larger

UNC0379

AOB6365

CAS No: 1620401-82-2

 

Chemical Name: 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

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$13.00

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $5.85 Total: $585.00
150 $6.76 Total: $338.00
125 $7.93 Total: $198.25
110 $9.36 Total: $93.60
15 $11.05 Total: $55.25

Data sheet

Molecular FormulaC23H35N5O2
Molecular Weight413.56
CAS Numbers1620401-82-2
Storage Condition0°C (short term), -20°C (long term), desiccated
Solubilitymore than 25 mg/mL/DMSO
Purity98% by HPLC

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A selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM

Reference:

Ma A, et al. Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8. J Med Chem. 2014 Aug 14;57(15):6822-33.

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