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ARI-3099 hydrochloride View larger

ARI-3099 hydrochloride

AOB4262

CAS: 1432499-49-4 (non-HCl salt)
 

Chemical Name: N-(Pyridine-4-carbonyl)-D-Ala-boroPro HCl; N-(Pyridine-4-carbonyl)-(R)-alaninyl-(R)-boroproline hydrochloride

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$49.50

$49.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $42.08 Total: $210.38
110 $35.64 Total: $356.40
125 $30.20 Total: $754.88
150 $25.74 Total: $1,287.00
1100 $22.28 Total: $2,227.50

Data sheet

Molecular FormulaC13H17BClN3O4
Molecular Weight325.56
CAS Numbers1432499-49-4 (free base)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymARI-3099 ; ARI3099; ARI 3099
IUPAC/Chemical NameB-[(2R)-1-[(2R)-1-Oxo-2-[(4-pyridinylcarbonyl)amino]propyl]-2-pyrrolidinyl]boronic acid hydrochloride
InChl KeyLCAILAILGOZQNE-SBSPUUFOSA-N
InChl CodeInChI=1S/C13H16BN3O4.ClH/c1-9(16-11(18)10-3-6-15-7-4-10)12(19)17-8-2-5-14(17)13(20)21;/h3-4,6-7,9H,2,5,8H2,1H3,(H,16,18)(H,20,21);1H/t9-;/m1./s1
SMILES CodeO=C(O)B1N(C([C@@H](C)NC(C2=CC=NC=C2)=O)=O)CCC1.[H]Cl
References1) Coppage AL, Heard KR, DiMare MT, Liu Y, Wu W, Lai JH, Bachovchin WW. Human FGF-21 Is a Substrate of Fibroblast Activation Protein. PLoS One. 2016 Mar 10;11(3):e0151269. doi: 10.1371/journal.pone.0151269. PubMed PMID: 26962859; PubMed Central PMCID: PMC4786124.2) Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, Wu Y, Zhou Y, Sudmeier JL, Sanford DG, Bachovchin WW. Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem. 2013 May 9;56(9):3467-77. doi: 10.1021/jm400351a. PubMed PMID: 23594271; PubMed Central PMCID: PMC4059180.

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Selective and Potent Inhibitor of Fibroblast Activation Protein and Prolyl Oligopeptidase









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