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ARI-3099 hydrochloride
AOB4262
CAS: 1432499-49-4 (non-HCl salt)
Chemical Name: N-(Pyridine-4-carbonyl)-D-Ala-boroPro HCl; N-(Pyridine-4-carbonyl)-(R)-alaninyl-(R)-boroproline hydrochloride
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $22.28 | Total: $2,227.50 |
| 1 | 50 | $25.74 | Total: $1,287.00 |
| 1 | 25 | $30.20 | Total: $754.88 |
| 1 | 10 | $35.64 | Total: $356.40 |
| 1 | 5 | $42.08 | Total: $210.38 |
Data sheet
| Molecular Formula | C13H17BClN3O4 |
| Molecular Weight | 325.56 |
| CAS Numbers | 1432499-49-4 (free base) |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | ARI-3099 ; ARI3099; ARI 3099 |
| IUPAC/Chemical Name | B-[(2R)-1-[(2R)-1-Oxo-2-[(4-pyridinylcarbonyl)amino]propyl]-2-pyrrolidinyl]boronic acid hydrochloride |
| InChl Key | LCAILAILGOZQNE-SBSPUUFOSA-N |
| InChl Code | InChI=1S/C13H16BN3O4.ClH/c1-9(16-11(18)10-3-6-15-7-4-10)12(19)17-8-2-5-14(17)13(20)21;/h3-4,6-7,9H,2,5,8H2,1H3,(H,16,18)(H,20,21);1H/t9-;/m1./s1 |
| SMILES Code | O=C(O)B1N(C([C@@H](C)NC(C2=CC=NC=C2)=O)=O)CCC1.[H]Cl |
| References | 1) Coppage AL, Heard KR, DiMare MT, Liu Y, Wu W, Lai JH, Bachovchin WW. Human FGF-21 Is a Substrate of Fibroblast Activation Protein. PLoS One. 2016 Mar 10;11(3):e0151269. doi: 10.1371/journal.pone.0151269. PubMed PMID: 26962859; PubMed Central PMCID: PMC4786124.2) Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, Wu Y, Zhou Y, Sudmeier JL, Sanford DG, Bachovchin WW. Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. J Med Chem. 2013 May 9;56(9):3467-77. doi: 10.1021/jm400351a. PubMed PMID: 23594271; PubMed Central PMCID: PMC4059180. |
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Selective and Potent Inhibitor of Fibroblast Activation Protein and Prolyl Oligopeptidase
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