Enzyme Inhibitors

PKM2-IN-1 View larger

PKM2-IN-1

AT4170

CAS 94164-88-2

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$29.00

$29.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.05 Total: $1,305.00
150 $15.08 Total: $754.00
125 $17.69 Total: $442.25
110 $20.88 Total: $208.80
15 $24.65 Total: $123.25

Data sheet

Molecular FormulaC18H19NO2S2
Molecular Weight345.48
CAS Numbers94164-88-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1=C(CSC(=S)N2CCCCC2)C(=O)c2ccccc2C1=O
ReferencesNing X, et al. Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase. Eur J Med Chem. 2017 Sep 29;138 343-352.

More info

PKM2-IN-1 (compound 3k) exhibits inhibitory activity against PKM2 with an IC50 of 2.95 ?M, while the IC50 for PKM1 is 4-5 times higher.