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INDY
AOB1261
Chemical Name: (1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2(3H)-ylidene)-2-propanone;
CAS No:1169755-45-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C12H13NO2S |
| Molecular Weight | 235.3 |
| CAS Numbers | 1169755-45-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO 20 mg per mL |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 1Z-(3-ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone |
| InChl Key | GCSZJMUFYOAHFY-SDQBBNPISA-N |
| InChl Code | InChI=1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3/b12-6- |
| SMILES Code | OC1=CC=C2C(N(CC)/C(S2)=C/C(C)=O)=C1 |
| References | 1) Ogawa, Y., Nonaka, Y., Goto, T., et al. Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. Nat. Commun. 1:86, (2010). 2) Wang, P., Alvarez-Perez, J.C., Felsenfeld, D.P., et al. A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication. Nat. Med. 21(4), 383-388 (2015). |
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Novel potent ATP-competitive Dyrk1A inhibitor
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