G Protein-Coupled Receptor Ligands

ML-SA5 View larger

ML-SA5

AOB11116

CAS: N/A

Chemical Name: N1-(3-Chloro-2-(piperidin-1-yl)phenyl)-N4,N4-dimethylbenzene-1,4-disulfonamide

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$59.00

$59.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $26.55 Total: $2,655.00
50 $30.68 Total: $1,534.00
25 $35.99 Total: $899.75
10 $42.48 Total: $424.80
5 $50.15 Total: $250.75

Data sheet

Molecular FormulaC19H24ClN3O4S2
Molecular Weight457.99
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymML-SA5; ML SA5; MLSA5
IUPAC/Chemical NameN1-(3-Chloro-2-(piperidin-1-yl)phenyl)-N4,N4-dimethylbenzene-1,4-disulfonamide
InChl KeyYPPWKTIVYUTTEH-UHFFFAOYSA-N
InChl CodeInChI=1S/C19H24ClN3O4S2/c1-22(2)29(26,27)16-11-9-15(10-12-16)28(24,25)21-18-8-6-7-17(20)19(18)23-13-4-3-5-14-23/h6-12,21H,3-5,13-14H2,1-2H3
SMILES CodeO=S(C1=CC=C(S(=O)(N(C)C)=O)C=C1)(NC2=CC=CC(Cl)=C2N3CCCCC3)=O
ReferencesLu et al. Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models, Science Advances 07 Feb 2020: Vol. 6, no. 6, eaaz2736 DOI: 10.1126/sciadv.aaz2736

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Novel mucolipin 1 (ML1) agonist, inducing lysosomal Ca2+ release, ameliorating muscular dystrophies and activating TFEB to correct lysosomal insufficiency in mdx mice