G Protein-Coupled Receptor Ligands

Protein Control Ligand
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G Protein-Coupled Receptor Ligands
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Nuclear Receptor Ligands
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Biomarkers and Buffer Solutions
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Alzheimer's Disease
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Ultra Pure Pharmacological Standard
Tissue Microarray (TMA)
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INT-747 (Obeticholic acid)

Cat No: AOB6610

Condition

CAS No:459789-99-2

More details

448 Item Items

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$11.05	Total: $55.25
1	10	$9.36	Total: $93.60
1	25	$7.93	Total: $198.25
1	50	$6.76	Total: $338.00
1	100	$5.85	Total: $585.00

Data sheet

Molecular Formula	C26H44O4
Molecular Weight	420.63
CAS Numbers	459789-99-2
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO
Purity	98% by HPLC
Synonym	6-Ethylchenodeoxycholic acid; Obeticholic acid; INT 747; INT-747; INT747; 6-ECDCA; Ocaliva.
IUPAC/Chemical Name	(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
InChl Key	ZXERDUOLZKYMJM-ZWECCWDJSA-N
InChl Code	InChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19+,20+,21+,23+,24-,25-,26-/m1/s1
SMILES Code	C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)[C@H](CC)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O
References	1) LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012 2) Fiorucci S, Di Giorgio C, Distrutti E. Obeticholic Acid: An Update of Its Pharmacological Activities in Liver Disorders. Handb Exp Pharmacol. 2019;256:283-295. doi: 10.1007/164_2019_227. Review. PubMed PMID: 31201552.