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Kinase Inhibitors
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THAL-SNS-032
AOB33255
CAS No: 2139287-33-3
Chemical Name: N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(14-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxo-6,9,12-trioxa-3-azatetradecyl)piperidine-4-carboxamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $18.68 | Total: $1,867.50 |
| 1 | 50 | $21.58 | Total: $1,079.00 |
| 1 | 25 | $25.32 | Total: $632.88 |
| 1 | 10 | $29.88 | Total: $298.80 |
| 1 | 5 | $35.28 | Total: $176.38 |
Data sheet
| Molecular Formula | C40H52N8O10S2 |
| Molecular Weight | 869.02 |
| CAS Numbers | 2139287-33-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | THAL-SNS-032; THALSNS032; THAL SNS 032; THAL-SNS 032; THAL SNS-032; THAL-SNS032; THALSNS-032 |
| IUPAC/Chemical Name | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(14-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxo-6,9,12-trioxa-3-azatetradecyl)piperidine-4-carboxamide |
| InChl Key | BXDZOYLPNAIDOC-UHFFFAOYSA-N |
| SMILES Code | CC(C)(C1=CN=C(O1)CSC2=CN=C(S2)NC(C3CCN(CC3)CC(NCCOCCOCCOCCNC4=C5C(N(C(C5=CC=C4)=O)C6CCC(NC6=O)=O)=O)=O)=O)C |
| References | Olson et al (2018) Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation. Nat.Chem.Biol. 14 163 PMID: 29251720 |
| PubChem ID | 131801483 |
More info
Novel selective CDK9 degrader consisting of a CDK-binding SNS-032 ligand linked to a thalidomide
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