Array
(
)
1
> Pathway Inhibitors>Enzyme Inhibitors>Kinase Inhibitors>BDP9066 Dihydrochloride

Kinase Inhibitors

BDP9066 Dihydrochloride View larger

BDP9066 Dihydrochloride

AOB36687

CAS: 2226507-04-4 (Base of S-Enantimer)

Chemical Name: 8-(3-(Pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane

More details

991 Items

Molarity Calculation Cart®

HOW TO ORDER

$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $26.35 Total: $131.75
110 $22.32 Total: $223.20
125 $18.91 Total: $472.75
150 $16.12 Total: $806.00
1100 $13.95 Total: $1,395.00

Data sheet

Molecular FormulaC20H26Cl2N6
Molecular Weight421.37
CAS Numbers2226507-04-4 (S-Enantiomer base)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBDP9066; BDP-9066; BDP 9066
IUPAC/Chemical Name8-(3-(Pyrimidin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane
InChl KeyUELSMLDRSQFVHG-FQEVSTJZSA-N
InChl CodeInChI=1S/C20H24N6/c1-2-8-25-20(6-1)7-3-11-26(13-20)17-5-10-22-19-18(17)15(12-23-19)16-4-9-21-14-24-16/h4-5,9-10,12,14,25H,1-3,6-8,11,13H2,(H,22,23)/t20-/m0/s1
SMILES CodeN(CCC1)(C2=C3C(NC=C3C4=NC=NC=C4)=NC=C2)C[C@@]51CCCCN5
References1) Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, Croft DR, Drysdale MJ, Garnett MJ, Gill K, Gray C, Greenhalgh DA, Hall JAM, Konczal J, Lilla S, McArthur D, McConnell P, McDonald L, McGarry L, McKinnon H, McMenemy C, Mezna M, Morrice NA, Munro J, Naylor G, Rath N, Schüttelkopf AW, Sime M, Olson MF. Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer. Cancer Res. 2018 Apr 15;78(8):2096-2114.

More info

Novel potent and selective MRCK inhibitor, reducing substrate phosphorylation, leading to morphological changes in cancer cells along with inhibition of their motility and invasive character

Customers who bought this product also bought: