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1-NA-PP1
AOB3852
CAS: 221243-82-9
Chemical Name: 1NA-PP1; PP1 Analog I; 4-Amino-1-tert-butyl-3-(1′-naphthyl)pyrazolo[3,4-d]pyrimidine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C24H27N5O3 |
| Molecular Weight | 433.5 |
| CAS Numbers | 1316214-52-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMF: 30 mg/ml DMF:PBS (pH 7.2) (1:5): 0.15 mg/ml DMSO: 1 mg/ml Ethanol: 2 mg/ml |
| Purity | 98% by HPLC |
| Synonym | 1-Naphthyl-PP1 PP1 Analog |
| IUPAC/Chemical Name | 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| InChl Key | XSHQBIXMLULFEV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H19N5/c1-19(2,3)24-18-15(17(20)21-11-22-18)16(23-24)14-10-6-8-12-7-4-5-9-13(12)14/h4-11H,1-3H3,(H2,20,21,22) |
| SMILES Code | NC1=C(C(C2=C(C=CC=C3)C3=CC=C2)=NN4C(C)(C)C)C4=NC=N1 |
| References | 1) Bishop, A.C., Kung, C.y., Shah, K., et al. Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach. J. Am. Chem. Soc. 121, 627-631 (1999). 2) Bishop, A.C., Ubersax, J.A., Petsch, D.T., et al. A chemical switch for inhibitor-sensitive alleles of any protein kinase. Nature 407, 395-401 (2000). |
More info
Potent, reversible, ATP-competitive, and cell-permeable inhibitor of Src-family tyrosine kinases