Kinase Inhibitors

GSK1120212 View larger

GSK1120212

AOB87707

CAS No:871700-17-3

Chemical Name: Trametinib, JTP-74057 

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$11.00

$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.95 Total: $495.00
150 $5.72 Total: $286.00
125 $6.71 Total: $167.75
110 $7.92 Total: $79.20
15 $9.35 Total: $46.75

Data sheet

Molecular FormulaC26H23FIN5O4
Molecular Weight615.39
CAS Numbers871700-17-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)

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A potent, highly selective and orally active inhibitor of MEK 1 and 2 inhibitor

References:

1: Gilmartin AG, Bleam MR, Groy A, Moss KG, et al., GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition, Clin Cancer Res. 2011 Jan 18. [Epub ahead of print]

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