Pathway Inhibitors

PI-273 View larger

PI-273

AOB37765

CAS: 925069-34-7

Chemical Name: 2-(3-(4-Chlorobenzoyl)thioureido)-4-ethyl-5-methylthiophene-3-carboxamide

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$25.00

$25.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.25 Total: $1,125.00
150 $13.00 Total: $650.00
125 $15.25 Total: $381.25
110 $18.00 Total: $180.00
15 $21.25 Total: $106.25

Data sheet

Molecular FormulaC16H16ClN3O2S2
Molecular Weight381.89
CAS Numbers925069-34-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymPI-273; PI273; PI 273
IUPAC/Chemical Name2-(3-(4-chlorobenzoyl)thioureido)-4-ethyl-5-methylthiophene-3-carboxamide
InChl KeyMIERMBQDBLFAFW-UHFFFAOYSA-N
InChl CodeInChI=1S/C16H16ClN3O2S2/c1-3-11-8(2)24-15(12(11)13(18)21)20-16(23)19-14(22)9-4-6-10(17)7-5-9/h4-7H,3H2,1-2H3,(H2,18,21)(H2,19,20,22,23)
SMILES CodeO=C(C1=C(NC(NC(C2=CC=C(Cl)C=C2)=O)=S)SC(C)=C1CC)N
References1) Li J, Gao Z, Zhao D, et al. PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells. Cancer Res. 2017;77(22):6253-6266. doi:10.1158/0008-5472.CAN-17-0484

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Novel, potent, specific, substrate-competitive inhibitor of PI4KIIα

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