Pathway Inhibitors

Pentachloropseudilin View larger

Pentachloropseudilin

AOB33969

CAS: 69640-38-6

 

Chemical Name: PClP; 2,4-Dichloro-6-(3,4,5-trichloro-1H-pyrrol-2-yl)phenol

AOBIOUS launched this product in 2019

CITATIONS - Publications That Use AOBIOUS Product

1) Blood Adv. 2024 May 1;8(17):4714–4726.

2) Cell Biology Oct 23, 2024

3) Blood Adv (2024) 8 (17): 4714–4726

4) Johns Hopkins University Thesis (2023)

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC10H4Cl5NO
Molecular Weight331.40
CAS Numbers69640-38-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymPentachloropseudilin; PClP
IUPAC/Chemical Name2,4-Dichloro-6-(3,4,5-trichloro-1H-pyrrol-2-yl)phenol
InChl KeyFBRLLYYPGGXCKT-UHFFFAOYSA-N
InChl CodeInChI=1S/C10H4Cl5NO/c11-3-1-4(9(17)5(12)2-3)8-6(13)7(14)10(15)16-8/h1-2,16-17H
SMILES CodeOC1=C(C2=C(Cl)C(Cl)=C(Cl)N2)C=C(Cl)C=C1Cl
References1) Chung CL, Wang SW, Martin R, Knölker HJ, Kao YC, Lin MH, Chen JJ, Huang YB, Wu DC, Chen CL. Pentachloropseudilin inhibits transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells. Chembiochem. 2018 Jan 25.

2) Gupta P, Martin R, Knölker HJ, Nihalani D, Kumar Sinha D. Myosin-1 inhibition by PClP affects membrane shape, cortical actin distribution and lipid droplet dynamics in early Zebrafish embryos. PLoS One. 2017 Jul 5;12(7)

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Selective Myosin-1 (Myo1) inhibitor, suppressing transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells

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