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TAK-981

AOB14037

CAS: 1858276-04-6

 

Chemical Name: ((1R,2S,4R)-4-((5-(4-((R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl)-5-methylthiophene-2-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate

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$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $41.65 Total: $208.25
110 $35.28 Total: $352.80
125 $29.89 Total: $747.25
150 $25.48 Total: $1,274.00
1100 $22.05 Total: $2,205.00

Data sheet

Molecular FormulaC25H28ClN5O5S2
Molecular Weight578.099
CAS Numbers1858276-04-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymTAK-981; TAK 981; TAK981;
IUPAC/Chemical Name[(1R,2S,4R)-4-[(5-[4-[(1R)-7-Chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl]pyrimidin-4-yl)amino]-2-hydroxycyclopentyl]methyl sulfamate
InChl KeyLXRZVMYMQHNYJB-UNXOBOICSA-N
InChl CodeInChI=1S/C25H28ClN5O5S2/c1-13-18(23-19-7-16(26)3-2-14(19)4-5-29-23)9-22(37-13)24(33)20-10-28-12-30-25(20)31-17-6-15(21(32)8-17)11-36-38(27,34)35/h2-3,7,9-10,12,15,17,21,23,29,32H,4-6,8,11H2,1H3,(H2,27,34,35)(H,28,30,31)/t15-,17-,21+,23+/m1/s1
SMILES CodeO=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=CC([C@@H]4NCCC5=C4C=C(Cl)C=C5)=C(C)S3)=O)C1)(N)=O
References1) ERIC S. LIGHTCAP et al., A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models, SCIENCE TRANSLATIONAL MEDICINE VOL. 13, NO. 611

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