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Pathway Inhibitors
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GDC-0941 (free base)
AOB87310
CAS No:957054-30-7
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HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $9.45 | Total: $945.00 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 5 | $17.85 | Total: $89.25 |
Data sheet
| Molecular Formula | C23H27N7O3S2 |
| Molecular Weight | 513.63 |
| CAS Numbers | 957054-30-7 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
More info
A potent and selective inhibitor of class I PI3 kinase (PI3K)
References:
1. Salphati L, Lee LB, Pang J, Plise EG, Zhang X. Role of P-glycoprotein and Breast Cancer Resistance Protein-1 in the Brain Penetration and Brain Pharmacodynamic Activity of the Novel PI3K Inhibitor GDC-0941. Drug Metab Dispos. 2010 Jun 3. [Epub ahead of print] PubMed PMID: 20522663.
2. Napper AD. Society for biomolecular sciences - 16th annual conference & exhibition - advancing the science of drug discovery. IDrugs. 2010 Jun;13(6):372-5.
3. O'Brien C, Wallin JJ, Sampath D, Guhathakurta D, Savage H, Punnoose EA, Guan J, Berry L, Prior WW, Amler LC, Belvin M, Friedman L, Lackner M. Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3' Kinase Inhibitor GDC-0941 In Breast Cancer Preclinical Models. Clin Cancer Res. 2010 May 7. [Epub ahead of print] PubMed PMID: 20453058.
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