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Cabozantinib (XL184, BMS-907351) View larger

Cabozantinib (XL184, BMS-907351)

AOB87755

CAS No: 849217-68-1

Chemical Name: N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

For Bulk quantities check : AOB87755B

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$18.00

$18.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $8.10 Total: $810.00
150 $9.36 Total: $468.00
125 $10.98 Total: $274.50
110 $12.96 Total: $129.60
15 $15.30 Total: $76.50

Data sheet

Molecular FormulaC28H24FN3O5
Molecular Weight501.5
CAS Numbers849217-68-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC

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A pan tyrosine kinase inhibitor that primarily targets VEGFR2 (IC50 = 0.035 nM) and c-Met (IC50 = 1.3 nM) but also inhibits RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively).