Protein Inhibitors

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AOB6713

CAS No: 1770789-37-1

Chemical Name: N-[4-(1-Oxo-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-yl)-butyl]-acetamide

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QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC17H21N3O2
Molecular Weight299.37
CAS Numbers1770789-37-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical NameN-[4-(1-Oxo-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-yl)-butyl]-acetamide
InChl KeyRYVLOOXFFIFQEN-UHFFFAOYSA-N
InChl Code InChI=1S/C17H21N3O2/c1-12(21)18-9-4-5-11-20-14-7-3-2-6-13(14)16-15(20)8-10-19-17(16)22/h2-3,6-7H,4-5,8-11H2,1H3,(H,18,21)(H,19,22)
SMILES CodeCC(NCCCCN1C(CCN2)=C(C2=O)C3=C1C=CC=C3)=O
References1) Gacias M, et al. Chem Biol. 17:841(2014)

2) Zhao L, et al., J Neuroinflammation. 19;14(1):14 (2017)

More info

Selective inhibitor of the first bromodomain of BET proteins, accelerating the progression of mouse primary oligodendrocyte progenitors toward differentiation, whereas inhibition of both bromodomains of BET proteins hindered differentiation

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