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Bz-423
AOB6435
CAS No: 216691-95-1
Chemical Name: 4-((4-(2-Fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-1-yl)-1,3,5-triazin-2-amine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $4.95 | Total: $495.00 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 5 | $9.35 | Total: $46.75 |
Data sheet
| Molecular Formula | C27H21ClN2O2 |
| Molecular Weight | 440.92 |
| CAS Numbers | 216691-95-1 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO 2 mg/mL |
| Purity | 98% by HPLC |
More info
An inhibitor of mitochondrial F1F0 ATP synthase. It binds the oligomycin sensitivity conferring protein (OSCP) component of mitochondrial F1F0-ATPase, resulting in superoxide generation and apoptosis. BZ-423 was shown to block multidrug-resistant melanoma cells. In another study, Bz-423 selectively increased superoxide and induced the apoptosis of alloreactive T cells, which arrested established Graft versus Host Disease