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SNJ-1945

Cat No: AOB36531

Condition

CAS: 854402-59-8

Chemical Name: ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester; SNJ1945

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$14.45	Total: $72.25
1	10	$12.24	Total: $122.40
1	25	$10.37	Total: $259.25
1	50	$8.84	Total: $442.00
1	100	$7.65	Total: $765.00

Data sheet

Molecular Formula	C25H37N3O7
Molecular Weight	491.59
CAS Numbers	854402-59-8
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO
Purity	98% by HPLC
Synonym	SNJ1945; SNJ 1945; SNJ-1945
IUPAC/Chemical Name	((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester
InChl Key	PMEQLUMDXFJNRY-SFTDATJTSA-N
InChl Code	InChI=1S/C25H37N3O7/c1-17(2)15-21(28-25(32)35-14-13-34-12-11-33-3)23(30)27-20(16-18-7-5-4-6-8-18)22(29)24(31)26-19-9-10-19/h4-8,17,19-21H,9-16H2,1-3H3,(H,26,31)(H,27,30)(H,28,32)/t20-,21-/m0/s1
SMILES Code	O=C(OCCOCCOC)N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(C(NC2CC2)=O)=O)=O)CC(C)C
References	1) Trager N, et al. Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis. J Neurochem. 2014 Jul;130(2):268-79. 2) Knaryan VH, et al. SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone. J Neurochem. 2014 Jul;130(2):280-90. 3) Bains M, et al. Pharmacological analysis of the cortical neuronal cytoskeletal protective efficacy of the calpain inhibitor SNJ-1945 in a mouse traumatic brain injury model. J Neurochem. 2013 Apr;125(1):125-32.