Enzyme Inhibitors

MRL-871 View larger

MRL-871

AOB0444

CAS No: 1392809-08-3

 

Chemical Name: 4-[1-[2-Chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl]-benzoic acid

More details

Molarity Calculation Cart®

HOW TO ORDER

$69.00

$69.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.05 Total: $3,105.00
150 $35.88 Total: $1,794.00
125 $42.09 Total: $1,052.25
110 $49.68 Total: $496.80
15 $58.65 Total: $293.25

Data sheet

Molecular FormulaC22H12ClF3N2O3
Molecular Weight444.79
CAS Numbers1392809-08-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymMRL-871; MRL 871; MRL871
IUPAC/Chemical Name4-[1-[2-Chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl]-benzoic acid
InChl KeyDANLZOIRUUHIIX-UHFFFAOYSA-N
InChl CodeInChI=1S/C22H12ClF3N2O3/c23-16-6-3-5-15(22(24,25)26)18(16)20(29)28-17-7-2-1-4-14(17)19(27-28)12-8-10-13(11-9-12)21(30)31/h1-11H,(H,30,31)
SMILES CodeO=C(O)C1=CC=C(C2=NN(C(C3=C(C(F)(F)F)C=CC=C3Cl)=O)C4=C2C=CC=C4)C=C1
ReferencesScheepstra M, Leysen S, van Almen GC, Miller JR, Piesvaux J, Kutilek V, van Eenennaam H, Zhang H, Barr K, Nagpal S, Soisson SM, Kornienko M, Wiley K, Elsen N, Sharma S, Correll CC, Trotter BW, van der Stelt M, Oubrie A, Ottmann C, Parthasarathy G, Brunsveld L. Identification of an allosteric binding site for RORγt inhibition. Nat Commun. 2015 Dec 7;6:8833. doi: 10.1038/ncomms9833. PubMed PMID: 26640126; PubMed Central PMCID: PMC4686831

More info

Novel RORγt inhibitor, binding to a previously unidentified allosteric pocket in the RORγt LBD

Customers who bought this product also bought: