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Kinase Inhibitors
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Masitinib
AOB87489
CAS No: 790299-79-5
Chemical Name: Masivet; AB-1010; 4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $2.25 | Total: $225.00 |
| 1 | 50 | $2.60 | Total: $130.00 |
| 1 | 25 | $3.05 | Total: $76.25 |
| 1 | 10 | $3.60 | Total: $36.00 |
| 1 | 5 | $4.25 | Total: $21.25 |
Data sheet
| Molecular Formula | C28H30N6OS |
| Molecular Weight | 498.65 |
| CAS Numbers | 790299-79-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | AB-1010; AB 1010; AB1010; Masitinib. Brand name: Kinavet; Masivet |
| IUPAC/Chemical Name | 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)benzamide |
| InChl Key | WJEOLQLKVOPQFV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32) |
| SMILES Code | O=C(NC1=CC=C(C)C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4 |
| References | Kocic I, Kowianski P, Rusiecka I, Lietzau G, Mansfield C, Moussy A, Hermine O, Dubreuil P. Neuroprotective effect of masitinib in rats with postischemic stroke. Naunyn Schmiedebergs Arch Pharmacol. 2015 Jan;388(1):79-86. |
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Potent and selective tyrosine kinase inhibitor targeting KIT
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