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> Pathway Inhibitors>Enzyme Inhibitors>Kinase Inhibitors>HTH-01-015

Kinase Inhibitors

HTH-01-015 View larger

HTH-01-015

AOB6634

CAS No:1613724-42-7

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$11.00

$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $9.35 Total: $46.75
110 $7.92 Total: $79.20
125 $6.71 Total: $167.75
150 $5.72 Total: $286.00
1100 $4.95 Total: $495.00

Data sheet

Molecular FormulaC26H28N8O
Molecular Weight468.55
CAS Numbers1613724-42-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymHTH01015; HTH 01 015
IUPAC/Chemical Name5,13-dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
InChl KeyCHSDJDLAKKAWCI-UHFFFAOYSA-N
InChl CodeInChI=1S/C26H28N8O/c1-16-23-24(31-26(29-16)30-19-14-28-34(15-19)20-8-10-27-11-9-20)32(2)22-13-18-7-5-4-6-17(18)12-21(22)25(35)33(23)3/h4-7,12-15,20,27H,8-11H2,1-3H3,(H,29,30,31)
SMILES CodeCC1=C(N(C)C(C2=CC(C=CC=C3)=C3C=C2N4C)=O)C4=NC(NC5=CN(N=C5)C6CCNCC6)=N1
References1) Banerjee, S., Buhrlage, S.J., Huang, H.T., et al. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochemistry Journal 457(1), 215-225 (2014).

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 A potent and selective inhibitor of NUAK1 

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