Kinase Inhibitors

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UNC1062

AOB4488

CAS No: 1350549-36-8

 

Chemical Name:4-[6-(Butylamino)-3-[4-(4-morpholinylsulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-cyclohexanol

AOBIOUS launched this product in 2013

CITATIONS - Publications That Use AOBIOUS Product

1) Oncotarget. 7:25698 (2016)

2) Oncotarget. 7:32678 (2016)

3) Dissertation (2015)

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Molarity Calculation Cart®

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$53.00

$53.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $23.85 Total: $2,385.00
50 $27.56 Total: $1,378.00
25 $32.33 Total: $808.25
10 $38.16 Total: $381.60
5 $45.05 Total: $225.25

Data sheet

Molecular FormulaC25H34N6O4S
Molecular Weight514.64
CAS Numbers1350549-36-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name4-[6-(butylamino)-3-(4-morpholin-4-ylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]cyclohexan-1-ol
InChl KeyKAAPXWSYROPAEL-UHFFFAOYSA-N
InChl CodeInChI=1S/C25H34N6O4S/c1-2-3-12-26-25-27-17-22-23(29-31(24(22)28-25)19-6-8-20(32)9-7-19)18-4-10-21(11-5-18)36(33,34)30-13-15-35-16-14-30/h4-5,10-11,17,19-20,32H,2-3,6-9,12-16H2,1H3,(H,26,27,28)
SMILES CodeCCCCNC1=NC=C2C(=NN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)S(=O)(=O)N5CCOCC5
References1) Schlegel J, et al. J Clin Invest. 123(5):2257-67 (2013).

2) Liu J, et al. Eur J Med Chem. 65:83-93 (2013).

3) von Mässenhausen A, et al. Oncotarget. 7(22):32678-94 (2016).

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Novel MERTK-selective tyrosine kinase inhibitor

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Citation (Publications used AOBIOUS products)

1) Oncotarget, Vol. 7, No. 22 (Received: January 07, 2016 Accepted: March 28, 2016 Published: April 13, 2016)

2) Dissertation (2015) - Entwicklung neuer Therapien in Tumoren des Kopf-Hals Bereichs

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